This article is the most comprehensive of the published resources available on monolaurin. The review was co-authored by the late Mary Enig, PhD who was one of the premier experts on dietary fats in the 20th century. This article highlights the need for natural antimicrobials due to rising resistance of microbes to various drugs, and reviews monolaurin and lauric acid’s chemistry, as well as their bactericidal, antifungal and virucidal effects.

Monolaurin is naturally found in breastmilk and is created when natural lipases found in breastmilk convert fats such as lauric acid into monoglyceride. It was demonstrated in this paper that the medium chain saturated fatty acids needed to be in their monoglyceride form to show disintegration of cellular and viral membranes. While not discussed directly in this paper, this conversion does not take place naturally in coconut oil. As demonstrated by the same authors in other papers, medium chain triglycerides such as lauric acid, need to be converted by lipases in digestion to their corresponding medium chain monoglycerides like monolaurin to be active against microbes.

Candida species are highly clinically relevant organsims that can be opportunistic in times of immune suppression.Microbes often excrete various virulence factors that can include the formation of biofilm. Biofilm protects the growth of the organism from outside agents and can increase resistance of the organism to botanical or pharmaceutical agents..This paper explores the antifungal and anti-inflammatory mechanisms of monolaurin on Candida albicans biofilm

The role of fat and heart disease has been controversial for many decades. This article examines the interplay of various types of fat and total cholesterol, LDL, HDL and other cardiovascular health markers. It also examines some research on how cardiovascular health may be affected when you consume trans fats, and when you substitute saturated fat with carbohydrates or polyunsaturated fats.

When you first start taking monolaurin, you can trigger flu-like symptoms that can be confused with an allergic reaction. Instead, it is an inflammatory and immune reaction to the killing of microbes known as a Jarisch-Herxheimer reaction. This reaction is a stress on the body and may be associated with stress-related symptoms as well. When a Jarisch-Herxheimer reaction occurs, it is recommended to decease the intake of monolaurin to a level that is tolerated.

Monoaurin discoverer Dr. Kabara explores the timeless use of coconut oil and its derivatives. He discusses the unique structure and function of medium chain fats when compared to other types of fats. He then details the clinical implications of coconut oil and monolaurin for dental caries, cancer, prostatic hyperplasia, gastric ulcers, as well as a special highlight on monolaurin’s effect on various viruses, bacteria, yeast, and protozoa.

The conversation regarding the association of fat intake and cancer has had a mixed, and largely negative past. The unique fats in coconut oil, and unique derivatives like monolaurin may offer protective properties against cancer development. This article explores how medium chain fats in coconut oil may protect against cancer development by supporting cell and membrane stability, promoting ketone generation, and maintaining immune health.

Borrelia species responsible for Lyme disease are difficult to treat in part because they present in various morphological forms: spirochetes, latent rounded forms and biofilm. Monolaurin was one of 15 plant-derived compounds evaluated in the study. The article concludes that of the compounds studied, monolaurin was one of the most effective antimicrobials against all three morphological forms of Borrelia burgdorferi and Borrelia garinii.

Coconut oil’s unique properties are largely determined by its high concentration of medium chain fats. Medium chain fats are a specific category of saturated fats that have unique properties when compared to short- and long-chain saturated fats. Much of the health discussion around saturated fats has focused on long-chain saturated fats (LCFAs). When you eat higher intake of LCFAs, you raise Total Cholesterol and LDL, but you also raise HDL to a higher degree – therefore key heart health ratios may improve. Medium chain fats do not require cholesterol to be carried around in the body, and help to boost metabolism. The net effect of coconut oil and medium chain fat consumption may be heart protective, or at worst heart risk-neutral.

Bruce Fife, ND, President and founder of the Coconut Research Center, wrote and presented this tribute to Dr. Jon J. Kabara when Dr. Kabara had passed away. Dr. Fife explores some of the story behind Dr. Kabara’s life and how his work greatly influenced the scientific discussion around fats and the unique nature of medium chain fats found and/or derived from coconut oil.

I've written a research paper on a possible treatment for COVID-19. This research was prompted by my own experience using the supplement Lauricidin, which was borderline miraculous. Please check it out and feel free to forward to anyone that may be interested - doctors, politicians, friends, etc.

This paper examines the full details of how monolaurin and other medium chain fats are digested and utilized by the body with supporting references. Due to this unique metabolism, medium chain fats have unique ketogenic and thermogenic properties that may help support fat burning and exercise performance.

This paper looks at how monolaurin helps decrease biofilm for Streptococcus mutans, Yersinia enterocolitica, Xanthomonas oryzae, but not for Aeromonas hydrophila. While monolaurin’s biofilm disrupting ability was largely believed to be related to its surfactant/detergent properties, this paper suggest that the biofilm inhibition can also be due to at least one other distinct mechanism.

Dental plaque is a “biofilm”-like substance that houses a range of bacteria. Collectively, these bacteria make acids that eat away at the structure of the tooth contributing to tooth loss, further bacterial and fungal growth, and gum disease.

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